Deciphering cancer fibroblasts.

Published in: The Journal of experimental medicine (2018)

In this issue of JEM, Raz et al. (https://doi.org/10.1084/jem.20180818) identify a subset of bone marrow-derived cells that uniquely promotes breast cancer angiogenesis and tumor growth. The existence of functional heterogeneity among stromal populations motivates further fundamental and therapeutic inquiries.

Keyphrases

induced apoptosis
papillary thyroid
cell cycle arrest
bone marrow
endothelial cells
squamous cell
single cell
mesenchymal stem cells
vascular endothelial growth factor
childhood cancer
signaling pathway
extracellular matrix
oxidative stress
cell proliferation