Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies.

Isabella CanazzaAndrea OssatoFabrizio VincenziAdolfo GregoriFabiana Di RosaFederica NigroAlessandro RimessiPaolo PintonKatia VaraniPier Andrea BoreaMatteo Marti

Published in: Human psychopharmacology (2017)

For the first time, the present study demonstrates the pharmaco-toxicological effects induced by the administration of 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice and suggests their possible detrimental effects on human health.

Keyphrases

human health
risk assessment
high fat diet induced
climate change
insulin resistance
skeletal muscle