Login / Signup

Whole-genome analysis of human papillomavirus genotypes 52 and 58 isolated from Japanese women with cervical intraepithelial neoplasia and invasive cervical cancer.

Yuri TenjimbayashiMamiko OnukiYusuke HiroseSeiichiro MoriYoshiyuki IshiiTakamasa TakeuchiNobutaka TasakaToyomi SatohTohru MorisadaTakashi IwataShingo MiyamotoKoji MatsumotoAkihiko SekizawaIwao Kukimoto
Published in: Infectious agents and cancer (2017)
Among the HPV52/58-positive specimens from Japanese women with CIN/ICC, the variant distributions were strongly biased toward lineage B for HPV52 and lineage A for HPV58 across histological categories. Different patterns of amino acid variations were observed in HPV52 and HPV58 across the viral whole-genome.
Keyphrases
  • high grade
  • cervical cancer screening
  • amino acid
  • single cell