Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study.
Alexis TabahNiccolò BuettiQuentin StaiqulyStéphane RucklyMurat AkovaAbdullah Tarik AslanMarc LeoneAndrew Conway MorrisMatteo BassettiKostoula ArvanitiJeffrey LipmanRicard FerrerHaibo QiuJosé-Artur PaivaPedro PovoaLiesbet De BusJan J De WaeleFarid ZandShreyas GutteAdel AlsisiKhalid AbidiHendrik BrachtYoshiro HayashiKyeongman JeonMuhammed ElhadiFrançois BarbierJean-François Timsitnull nullPublished in: Intensive care medicine (2023)
HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes.
Keyphrases
- antimicrobial resistance
- gram negative
- end stage renal disease
- intensive care unit
- ejection fraction
- newly diagnosed
- multidrug resistant
- chronic kidney disease
- staphylococcus aureus
- peritoneal dialysis
- risk factors
- stem cells
- type diabetes
- skeletal muscle
- adipose tissue
- patient reported outcomes
- metabolic syndrome
- cardiovascular events
- mesenchymal stem cells
- bone marrow
- patient reported
- mechanical ventilation
- smoking cessation
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation