The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts.

Nisha VenugopalAnanga GhoshHardik P Gala Ajoy Aloysius Neha Vyas Jyotsna Dhawan

Published in: BMC molecular and cell biology (2020)

Taken together, our results show that the primary cilium integrates and dampens proliferative signaling, represses translation and G2/M genes, and is integral to the establishment of the quiescence program.

Keyphrases

gene expression
transcription factor
quality improvement
dna methylation