Glyphosate Use and Mosaic Loss of Chromosome Y among Male Farmers in the Agricultural Health Study.
Vicky C ChangWeiyin ZhouSonja I BerndtGabriella AndreottiMeredith YeagerChristine G ParksDale P SandlerNathaniel RothmanLaura E Beane FreemanMitchell J MachielaJonathan N HofmannPublished in: Environmental health perspectives (2023)
High lifetime glyphosate use could be associated with mLOY affecting a larger fraction of cells, suggesting glyphosate could confer genotoxic or selective effects relevant for clonal expansion. As the first study to investigate this association, our findings contribute novel evidence regarding the carcinogenic potential of glyphosate and require replication in future studies. https://doi.org/10.1289/EHP12834.