Structural network efficiency predicts conversion to incident parkinsonism in patients with cerebral small vessel disease.
Mengfei CaiMina A JacobJosé MarquesDavid G NorrisMarco DueringRianne A J EsselinkYuhu ZhangFrank-Erik de LeeuwAnil M TuladharPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
Our findings suggest that global network efficiency is associated with a gradual decline in motor performance, ultimately leading to incident parkinsonism in the elderly with SVD. Global network efficiency may have the added value to serve as a useful marker to capture changes of motor signs.