Cytokine profile in the sputum of subjects with post-tuberculosis airflow obstruction and in those with tobacco related chronic obstructive pulmonary disease.
Elise GuiedemEric Walter Pefura-YoneGeorge Mondinde IkomeyCéline Nguefeu NkenfouMartha MesembeMbanyamsig Mispa YivalaBih Hycenta ChendiGraeme Brendon JacobsNovel Njweipi ChegouMarie Claire Assoumou OkomoPublished in: BMC immunology (2020)
COPD related to tobacco is more severe than post-TB airflow obstruction. The pathogenesis of post-TB airflow obstruction appears to involve the cytokines IL-1RA, IL-1α, IL-1β, IL-17, GRO and sCD40L, while COPD related to tobacco involves more cytokines.