Patient Perspectives of the Manifestations and Treatment of Anti-MDA5 Antibody-Positive Dermatomyositis: An Observational Survey.
Timothy KanieckiBenita MoyersManuel LubinusYuan-Pai HuLynn WilsonStephen MooreJerry WilliamsLisa Christopher-StinePublished in: The Journal of rheumatology (2024)
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of autoimmune disorders classically characterized by proximal skeletal muscle inflammation leading to weakness, but they often possess additional systemic manifestations such as cutaneous, pulmonary, and articular disease. 1 Although originally dichotomized as either dermatomyositis (DM) or polymyositis, the discovery of new myositis-specific antibodies (MSA) and myositis-associated antibodies has led to the delineation of more refined IIM patient subgroups.
Keyphrases
- interstitial lung disease
- systemic sclerosis
- skeletal muscle
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- oxidative stress
- case report
- multiple sclerosis
- pulmonary hypertension
- small molecule
- high throughput
- insulin resistance
- breast cancer cells
- myasthenia gravis
- weight loss
- metabolic syndrome
- cell death
- drug induced
- cell proliferation
- single cell
- pi k akt