A Photoredox Coupling Reaction of Benzylboronic Esters and Carbonyl Compounds in Batch and Flow.

Henrique A EstevesOliver MayDavid C BlakemoreSteven V Ley

Published in: Organic letters (2019)

Mild cross-coupling reaction between benzylboronic esters with carbonyl compounds and some imines was achieved under visible-light-induced iridium-catalyzed photoredox conditions. Functional group tolerance was demonstrated by 51 examples, including 13 heterocyclic compounds. Gram-scale reaction was realized through the use of computer-controlled continuous flow photoreactors.

Keyphrases

room temperature
electron transfer
visible light
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anaerobic digestion