mRNA vaccine against fibroblast activation protein ameliorates murine models of inflammatory arthritis.

Xiaowei ZhangAntony JozicPingfang SongQiang XuXiaofei ShiHong WangLindsey BishopHillary M StruthersJohn RutledgeShuang ChenFei XuMeaghan H HancockDaocheng ZhuGaurav SahayCong-Qiu Chu

Published in: Rheumatology and immunology research (2023)

cFAP mRNA-LNP vaccine was able to provoke immune response to mFAP and suppress inflammatory arthritis.

Keyphrases

rheumatoid arthritis
binding protein
oxidative stress
mouse model
amino acid
small molecule