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Perillyl alcohol modulates activation, permeability and integrity of human brain endothelial cells induced by Plasmodium falciparum.

Adriana A MarinAnnette JuillardAlejandro M KatzinLeonardo J M CarvalhoGeorges Emile Raymond Grau
Published in: Memorias do Instituto Oswaldo Cruz (2023)
POH is a potent monoterpene that is efficient in preventing P. falciparum-pRBCs-induced changes in HBEC, namely their activation, increased permeability and alterations of integrity, all parameters of relevance to CM pathogenesis.
Keyphrases
  • endothelial cells
  • plasmodium falciparum
  • high glucose
  • vascular endothelial growth factor
  • anti inflammatory