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Biological Augments for Acetabular Chondral Defects in Hip Arthroscopy-A Scoping Review of the Current Clinical Evidence.

Johnny RayesSara SparavaloIvan H Wong
Published in: Current reviews in musculoskeletal medicine (2021)
Increasing evidence is available for different biological solutions used in the hip. Studies have shown promising outcomes with minimal complications when using biologics as augmentation to microfracture (MF), including different scaffolds or stem cells, or to enhance autologous chondrocyte implantation (ACI). However, data so far is scarce, and more trials and longer follow-ups are needed to better delineate the appropriate indications and benefits for each technique. Presently, the level of evidence is low, but in general, biologics appear safe and trend toward beneficial compared to standard surgical techniques. Augmented MF is recommended for small to medium ACDs, and matrix-assisted ACI or three-dimensional ACI is recommended for medium to large defects.
Keyphrases
  • stem cells
  • total hip arthroplasty
  • cell therapy
  • bone marrow
  • type diabetes
  • risk factors
  • metabolic syndrome
  • insulin resistance
  • weight loss
  • soft tissue