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Early safety of tenofovir alafenamide in patients with a history of tubulopathy on tenofovir disoproxil fumarate: a randomized controlled clinical trial.

L HamzahD WilliamsA C BaileyR JonesF IbrahimC G MussoK BurlingB BarbiniL CampbellFrank A Postnull null
Published in: HIV medicine (2019)
In people with a history of proximal renal tubulopathy while on TDF, 12-week exposure to TAF did not adversely affect renal tubular function. These data support continued evaluation of the long-term safety of TAF in this group of patients.
Keyphrases
  • end stage renal disease
  • newly diagnosed
  • ejection fraction
  • chronic kidney disease
  • peritoneal dialysis
  • antiretroviral therapy
  • prognostic factors
  • machine learning
  • big data
  • artificial intelligence