Label-free histomorphometry of peripheral nerve by stimulated Raman spectroscopy.
Iván Coto HernándezWenlong YangSuresh MohanNate JowettPublished in: Muscle & nerve (2020)
Herein, we demonstrate the use of a label-free technique for rapid imaging of murine and human peripheral nerve cryosections. We illustrate the potential of this technique to inform intraoperative decision-making through rapid automated quantification of myelinated axons using a machine learning algorithm.
Keyphrases
- peripheral nerve
- label free
- machine learning
- raman spectroscopy
- decision making
- deep learning
- endothelial cells
- artificial intelligence
- loop mediated isothermal amplification
- big data
- high resolution
- induced pluripotent stem cells
- high throughput
- patients undergoing
- risk assessment
- mass spectrometry
- quantum dots
- neural network
- climate change