Respiratory and nonrespiratory COVID-19 complications in patients with obesity: recent developments.
Esther LiuHudson LeeBriana LuiRobert S WhiteMarguerite M HoylerPublished in: Journal of comparative effectiveness research (2022)
This narrative review summarizes recent reports to provide an updated understanding of the multiorgan effects of SARS-CoV-2 infection in obese individuals. A PubMed search of 528 primary articles was performed, with inclusion based on novelty, relevance and redundancy. Obesity confers an increased risk for hospitalization, intensive care unit admission, severe pneumonia, intubation and acute kidney injury in COVID-19 patients. Obesity is also associated with higher levels of inflammatory and thrombotic markers. However, the associations between obesity and mortality or cardiac injury in COVID-19 patients remain unclear. Obesity is a risk factor for several respiratory and nonrespiratory COVID-19 complications. Future work is needed to further explore these relationships and optimize the management of obese COVID-19 patients.
Keyphrases
- weight loss
- metabolic syndrome
- sars cov
- insulin resistance
- type diabetes
- high fat diet induced
- intensive care unit
- weight gain
- coronavirus disease
- bariatric surgery
- adipose tissue
- risk factors
- emergency department
- respiratory syndrome coronavirus
- heart failure
- left ventricular
- body mass index
- coronary artery disease
- cardiovascular disease
- mechanical ventilation
- atrial fibrillation
- respiratory failure