Persistent systemic rotavirus vaccine infection in a child with X-linked severe combined immunodeficiency.
Tetsushi YoshikawaMasaru IhiraYuki HigashimotoFumihiko HattoriHiroki MiuraKen SugataSatoshi KomotoKoki TaniguchiAkihiro IguchiMasafumi YamadaTadashi ArigaPublished in: Journal of medical virology (2019)
The kinetics of RVA RNA load in serum and stool samples was consistent with the clinical course of the patient. Among five genotypes of RV5 vaccine, G1 genotype replicated well in this patient. Reassortment and rearrangements were demonstrated in persistently infected G1 genotype of RV5.