Genome-wide association study identifies genetic variants which predict the response of bone mineral density to teriparatide therapy.
Nerea AlonsoOmar M E AlbaghaAsim AzferBeatriz Larraz-PrietoKathryn BergPhilip L RichesBarbara OstanekTomaz KocjanJanja MarcBente L LangdahlStuart H RalstonPublished in: Annals of the rheumatic diseases (2023)
Genetic factors influence the response to TPTD at the lumbar spine and hip with a magnitude of effect that is clinically relevant. Further studies are required to identify the causal genetic variants and underlying mechanisms as well as to explore how genetic testing for these variants might be implemented in clinical practice.