Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma.

Ramon Francisco Barajas Daniel Schwartz Heather L McConnell Cymon N Kersch Xin Li B E Hamilton Jay Starkey David R Pettersson Joshua P Nickerson Jeffrey Michael Pollock Rongwei Fu A Horvath L Szidonya C G Varallyay Jerry J Jaboin Ahmed A Raslan Aclan Dogan Justin S Cetas J Ciporen Seunggu Jude Han Prakash Ambady Leslie L Muldoon Randall L Woltjer William D Rooney Edward A Neuwelt

Published in: AJNR. American journal of neuroradiology (2020)

Segregation and extravascular localization of ferumoxytol MR imaging improves on current techniques by eliminating intrinsic tissue and intravascular ferumoxytol signal and may inform glioblastoma outcomes by serving as a more specific metric of macrophage content compared with uncorrected T1 and SWI techniques.

Keyphrases

coronary artery
adipose tissue
white matter
resting state
contrast enhanced
cerebral ischemia
blood brain barrier
brain injury
subarachnoid hemorrhage