Chronic hepatitis B virus infection drives changes in systemic immune activation profile in patients coinfected with Plasmodium vivax malaria.
Luís A B CruzMarina O A MoraesMatheus R Queiroga-BarrosKiyoshi F FukutaniManoel Barral-NettoBruno Bezerril AndradePublished in: PLoS neglected tropical diseases (2019)
The findings demonstrate a distinct inflammatory profile in coinfected patients, with characteristics associated with immune responses to both pathogens. These host responses to P. vivax and HBV, in conjunction, could be potentially associated, if not mainly responsible, for the protection against symptomatic vivax malaria.