Urine tricarboxylic acid cycle signatures of early-stage diabetic kidney disease.

Joseph LunyeraClarissa J DiamantidisHayden B BosworthUptal D PatelJames BainMichael J MuehlbauerOlga IlkayevaMaggie NguyenBinu SharmaJennie Z MaSvati H ShahJulia J Scialla

Published in: Metabolomics : Official journal of the Metabolomic Society (2021)

Thus, lower urine TCA cycle OAs, most notably lower methylmalonate, ethylmalonate and citrate/isocitrate, are potential indicators of kidney impairment in early stage DKD.

Keyphrases

early stage
sentinel lymph node
type diabetes
genome wide
wound healing
gene expression
risk assessment
lymph node
radiation therapy
dna methylation