Oxaliplatin-induced increase in splenic volume: experiences from multicenter study in Japan.
Ryo OhtaTakeshi YamadaKeisuke HaraTakuma IwaiKohji TanakayaKeiichiro IshibashiKazuhiko YoshimatsuChihiro KosugiMasahiro TsubakiHideo NakajimaMasatoshi OyaHiroshi YoshidaKeiji KodaHideyuki IshidaPublished in: International journal of clinical oncology (2020)
This study can be verified the findings observed in our previous single-center study, oxaliplatin-based adjuvant chemotherapy was associated with an increase in SV. Furthermore, this increase can persist for > 1 year. The continuous presence of SOS may have a negative impact on prognosis in patients that develop recurrent disease.