Longitudinal TNFR1 and TNFR2 and Kidney Outcomes: Results from AASK and VA NEPHRON-D.
Teresa K ChenSteven G CocaMichelle M EstrellaLawrence J AppelJosef CoreshHeather R Thiessen-PhilbrookWassim ObeidLinda F FriedHiddo J Lambers HeerspinkJoachim H IxMichael G ShlipakPaul L KimmelChirag R ParikhMorgan E Gramsnull nullPublished in: Journal of the American Society of Nephrology : JASN (2022)
Among individuals with and without diabetes, longitudinal increases in TNFR1 and TNFR2 were each associated with progressive CKD, independent of initial biomarker level and kidney function.