Correlation of Tumor Immunohistochemistry with Dynamic Contrast-Enhanced and DSC-MRI Parameters in Patients with Gliomas.
Thanh Binh NguyenG O CronK BezzinaKirstin A PerdrizetCarlos TorresSantanu ChakrabortyJohn WoulfeGerard H JansenRebecca E ThornhillBrandon ZanetteI G CameronPublished in: AJNR. American journal of neuroradiology (2016)
With dynamic contrast-enhanced MR imaging, use of a phase-derived vascular input function and bookend T1 mapping improves the correlation between immunohistochemistry and plasma volume, but not between immunohistochemistry and the volume transfer constant. With DSC-MR imaging, normalization of tumor CBV could decrease the correlation with microvessel area.