Correlation of Tumor Immunohistochemistry with Dynamic Contrast-Enhanced and DSC-MRI Parameters in Patients with Gliomas.

Thanh Binh Nguyen G O Cron K Bezzina Kirstin A Perdrizet Carlos Torres Santanu Chakraborty John M Woulfe Gerard H Jansen Rebecca E Thornhill Brandon Zanette I G Cameron

Published in: AJNR. American journal of neuroradiology (2016)

With dynamic contrast-enhanced MR imaging, use of a phase-derived vascular input function and bookend T1 mapping improves the correlation between immunohistochemistry and plasma volume, but not between immunohistochemistry and the volume transfer constant. With DSC-MR imaging, normalization of tumor CBV could decrease the correlation with microvessel area.

Keyphrases

contrast enhanced
magnetic resonance imaging
high resolution
high grade
computed tomography
magnetic resonance
diffusion weighted imaging
mass spectrometry
high density