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Dietary corn resistant starch regulates intestinal morphology and barrier functions by activating the Notch signaling pathway of broilers.

Yingying ZhangYingsen LiuJiaolong LiTong XingYun JiangLin ZhangFeng Gao
Published in: Asian-Australasian journal of animal sciences (2020)
These findings suggested that RS could suppress intestinal morphology and barrier functions by activating Notch pathway and inhibiting the development of goblet cells, resulting in decreased mucins and tight junction mRNA expression.
Keyphrases
  • signaling pathway
  • induced apoptosis
  • pi k akt
  • cell cycle arrest
  • epithelial mesenchymal transition
  • cell proliferation
  • blood brain barrier
  • endoplasmic reticulum stress
  • cell death