Epithelial-mesenchymal transition-related serum markers ET-1, IL-8 and TGF-β2 are elevated in a Finnish wet age-related macular degeneration cohort.
Mikko P K LiukkonenJussi J PaternoNiko KivinenLeea SiintamoAli K J KoskelaKai KaarnirantaPublished in: Acta ophthalmologica (2021)
ET-1, IL-8 and TGF-β2 appear to be useful serum biomarkers in understanding active wet AMD. However, we cannot conclude that local retinal EMT-processes could be observed from the corresponding systemic serum biomarkers in patients undergoing anti-VEGF-A treatments.