Comment on "Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice".

Yuanyuan WangMartin WeberOded ForemanHelga RemyEva Zsuzsanna Mracsko Jesse E Hanson

Published in: Science translational medicine (2023)

We highlight potential issues with a Western blot assay using mouse anti-caspase-1 antibody to detect cleaved caspase-1 p20 subunit in mouse brain tissue lysates.

Keyphrases

cell death
induced apoptosis
high throughput
south africa
high fat diet induced
endoplasmic reticulum stress
oxidative stress
mouse model
type diabetes
climate change
insulin resistance