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Vitamin B 12 deficiency presenting as neck pain and cervical radiculopathy.

Ashin MehtaWhitney LynchPinky Jha
Published in: BMJ case reports (2024)
Vitamin B 12 is required for the formation of haematopoietic cells and the synthesis of myelin. Deficiency typically presents with fatigue and megaloblastic anaemia. Prolonged deficiency can cause neurological symptoms such as paresthesia, which can progress to subacute combined degeneration of the spinal cord. We describe an unusual presentation of B 12 deficiency in a young man who was initially diagnosed and treated for cervical radiculopathy. This case highlights the challenges of diagnosing B 12 deficiency in patients with neurologic but without haematologic, abnormalities. While the current incidence of B 12 deficiency in developed countries is low, cases are likely to rise with the increased adoption of veganism. Clinicians should be aware of the variable presentations of B 12 deficiency because delayed diagnosis and treatment increases morbidity and can cause irreversible neurological deficits.
Keyphrases
  • spinal cord
  • replacement therapy
  • traumatic brain injury
  • induced apoptosis
  • spinal cord injury
  • sleep quality
  • physical activity
  • multiple sclerosis
  • middle aged