Diffuse sclerosing variant of papillary thyroid carcinoma: major genetic alterations and prognostic implications.

Ji Y JoungBongseong KimDae J JeongSun-Mi ParkYoon Y ChoHye W JangYoon Y JungYoung L OhHyun S YimYoo-Li KimJae H ChungChang-Seok KiSun W Kim

Published in: Histopathology (2016)

Taken together, RET/PTC rearrangement was the major genetic alteration seen in patients with DSV-PTC, and the RET/PTC3 rearrangement was associated with advanced stage at diagnosis and poor clinical outcome.

Keyphrases

genome wide
lymph node
copy number
low grade
squamous cell carcinoma
dna methylation
gene expression