Targeted metabolic profiling rapidly differentiates Escherichia coli and Staphylococcus aureus at species and strain level.
Haorong LiJiangjiang ZhuPublished in: Rapid communications in mass spectrometry : RCM (2018)
A targeted metabolomics method was developed to demonstrate the utility of HPLC/MS/MS-based metabolic profiling in rapidly (4 h) differentiating E. coli and S. aureus bacteria, two of the most notorious foodborne bacteria, at both the species and strain/serovar levels. The results indicated that our approach has great potential in the future for fast and specific detection of foodborne pathogenic bacteria based on their metabolic diversity.
Keyphrases
- ms ms
- escherichia coli
- staphylococcus aureus
- mass spectrometry
- cancer therapy
- single cell
- biofilm formation
- current status
- simultaneous determination
- high performance liquid chromatography
- genetic diversity
- magnetic resonance imaging
- drug delivery
- computed tomography
- multidrug resistant
- high resolution
- klebsiella pneumoniae
- tandem mass spectrometry
- human health
- sensitive detection
- quantum dots
- liquid chromatography