Neoadjuvant Treatments for Advanced Resectable Melanoma.
Jessica Y LiuMichael C LowePublished in: Journal of surgical oncology (2018)
Neoadjuvant therapy has demonstrated promise as a treatment modality in resectable advanced-stage melanoma. Treatment has evolved beyond chemotherapy, with the utilization of biochemotherapy, immunotherapy, and targeted therapy in the neoadjuvant setting. These therapies have shown better progression-free survival and melanoma-specific survival when compared with patients that proceed directly to surgery. Ongoing clinical trials will continue to propel research forward to improve the available options for patients with resectable advanced regional disease.
Keyphrases
- locally advanced
- rectal cancer
- free survival
- clinical trial
- squamous cell carcinoma
- lymph node
- radiation therapy
- end stage renal disease
- minimally invasive
- newly diagnosed
- ejection fraction
- chronic kidney disease
- stem cells
- peritoneal dialysis
- skin cancer
- combination therapy
- machine learning
- patient reported outcomes
- percutaneous coronary intervention
- open label