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An ambient-temperature storage and stabilization device performs comparably to flash-frozen collection for stool metabolomics in infants.

Sivapriya RamamoorthyShira LevyMasouma MohamedAlaa AbdelghaniAnne M EvansLuke A D MillerLopa MehtaSean MooreElizaveta FreinkmanSuchitra K Hourigan
Published in: BMC microbiology (2021)
Ambient temperature storage and stabilization of stool in the OMNImet.GUT device yielded comparable metabolomic results to flash freezing in terms of 1) the identity and abundance of detected biochemicals 2) the distinct metabolomic profiles of subjects and 3) changes in metabolites over time that are plausibly microbiota-induced. This method potentially provides a more convenient, less expensive home collection and storage option for stool metabolomic analysis.
Keyphrases
  • air pollution
  • particulate matter
  • healthcare
  • mass spectrometry
  • ms ms
  • high glucose
  • microbial community
  • wastewater treatment
  • data analysis