Lower levels of vWF are associated with lower risk of cardiovascular disease.
Pauline C S van ParidonMarina Panova-NoevaRene van OerleAndreas SchulzJürgen H ProchaskaNatalie ArnoldIrene SchmidtmannManfred BeutelNorbert PfeifferThomas MünzelKarl J LacknerHugo Ten CatePhilipp S WildHenri M H SpronkPublished in: Research and practice in thrombosis and haemostasis (2022)
The study demonstrated that having low vWF activity levels were associated with a lower risk for CVD. Additionally, it revealed a decreased risk of cardiovascular and all-cause mortality in individuals with low levels of vWF antigen, shining new light on vWF as a potential target for novel therapies.