Association of a blood-based aging biomarker index with death and chronic disease: Cardiovascular Health Study.
Xiao ZhangJason L SandersRobert M BoudreauAlice M ArnoldJamie Nicole JusticeMark A EspelandGeorge A KuchelNir BarzilaiLewis H KullerOscar L LopezStephen B KritchevskyAnne B NewmanPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
BI was significantly and independently associated with a composite outcome of death and chronic disease, and attenuated the effect of age. The BI that is composed of plasma biomarkers may be a practical intermediate phenotype for interventions aiming to modify the course of aging.
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