Tri-mannose grafting of chitosan nanocarriers remodels the macrophage response to bacterial infection.

Juan Manuel CoyaLaura De MatteisAlexandre Giraud-GatineauAnne BitonInés Serrano-SevillaAnne DanckaertMarie-Agnès DilliesBrigitte GicquelJesus M De la FuenteLudovic Tailleux

Published in: Journal of nanobiotechnology (2019)

The ability to modulate cell metabolism by grafting ligands at the surface of nanoparticles may thus be a promising strategy to reprogram immune cells and improve the efficacy of encapsulated drugs.

Keyphrases

drug delivery
single cell
cell therapy
breast reconstruction
adipose tissue
cancer therapy
drug release
stem cells
wound healing
mesenchymal stem cells