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Investigating the Role of Neighborhood Socioeconomic Status and Germline Genetics on Prostate Cancer Risk.

Jonathan JuddJeffrey P SpenceJonathan K PritchardLinda KachuriJohn S Witte
Published in: medRxiv : the preprint server for health sciences (2024)
We reaffirmed genetics as a risk factor for PCa and identified nSES deprivation domains that influence PCa detection and are potentially correlated with environmental exposures that are a risk factor for PCa. These findings also suggest that nSES and genetic risk factors for PCa act independently.
Keyphrases
  • prostate cancer
  • radical prostatectomy
  • physical activity
  • air pollution
  • copy number
  • dna methylation
  • gene expression
  • dna damage
  • life cycle