Cerebral effects of glucagon-like peptide-1 receptor blockade before and after Roux-en-Y gastric bypass surgery in obese women: A proof-of-concept resting-state functional MRI study.
Eelco van DuinkerkenGabriel BernardesLiselotte van BloemendaalDick J VeltmanFrederik BarkhofDaniel C MograbiVictor E A GerdesCarolyn F DeaconJens J HolstMadeleine L DrentMichaela DiamantJennifer Ten KulveRichard G IjzermanPublished in: Diabetes, obesity & metabolism (2020)
These findings suggest GLP-1 involvement in resting-state networks related to food and reward processes and monitoring of the internal and external environment, pointing to a potential role for GLP-1-induced changes in resting-state connectivity in RYGB-mediated weight loss and appetite control.
Keyphrases
- resting state
- weight loss
- roux en y gastric bypass
- functional connectivity
- bariatric surgery
- gastric bypass
- obese patients
- minimally invasive
- glycemic control
- magnetic resonance imaging
- polycystic ovary syndrome
- coronary artery bypass
- weight gain
- subarachnoid hemorrhage
- adipose tissue
- contrast enhanced
- type diabetes
- multiple sclerosis
- computed tomography
- human health
- skeletal muscle
- body mass index
- percutaneous coronary intervention
- drug induced
- diffusion weighted imaging
- blood brain barrier
- coronary artery disease
- binding protein
- white matter