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Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment.

Liliana R LoureiroLydia HoffmannChristin NeuberLuise RuppClaudia ArndtAlexandra KeglerManja KubeilChristoph E HagemeyerHolger StephanMarc SchmitzAnja FeldmannMichael Philipp Bachmann
Published in: Journal of experimental & clinical cancer research : CR (2023)
These findings demonstrate that the novel αFAP TMs are promising immunotheranostic tools to foster cancer imaging and treatment, paving the way for a more convenient, individualized, and safer treatment of cancer patients.
Keyphrases
  • high resolution
  • induced apoptosis
  • papillary thyroid
  • signaling pathway
  • endoplasmic reticulum stress