A Seminested PCR Method for the Diagnosis of Invasive Fungal Infections in Combat Injured.
Graham C EllisFaraz ShaikhM Leigh CarsonErica SercyLaveta StewartJared M AndrewsWesley R CampbellKatrin MendeJoseph M YabesDavid R TribbleRalf BialekBrian L WickesAnuradha GanesanPublished in: Open forum infectious diseases (2024)
Prior studies of seminested molecular diagnostics have focused on culture-negative samples from immunocompromised patients. Our findings underscore the utility of the seminested approach in diagnosing soft-tissue IFIs using formalin-fixed paraffin-embedded tissue samples, especially with angioinvasion.