Planning for success: overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial.

Louise RoperMark D LyttleCarrol GambleAmy HumphreysShrouk MessahelElizabeth D LeeJoanne NobletHelen HickeyNaomi RainfordAnand IyerRichard AppletonKerry Woolfall

Published in: Emergency medicine journal : EMJ (2020)

Successful trial recruitment and conduct in a challenging ED-led trial was driven by trial design, recruitment experience, teamwork and leadership. Our study provides valuable insight from parents and practitioners to inform the design and conduct of future trials in this setting.

Keyphrases

emergency department
phase iii
study protocol
phase ii
clinical trial
primary care
intensive care unit
open label
adverse drug
drug induced