Increased serum QUIN/KYNA is a reliable biomarker of post-stroke cognitive decline.
Adrien CogoGabrielle ManginBenjamin MaïerJacques CallebertMikael MazighiHughes ChabriatJean-Marie LaunayGilles HuberfeldNathalie KubisPublished in: Molecular neurodegeneration (2021)
we have established and characterized a new model of PSCI, functionally and structurally, and we have shown that the QUIN/KYNA ratio could be used as a surrogate biomarker of PSCI, which may now be tested in large prospective studies of stroke patients.