Species, antibiotic susceptibility profiles and van gene frequencies among enterococci isolated from patients at Mulago National Referral Hospital in Kampala, Uganda.
David Patrick KateeteMoses EdoluEdgar KigoziJeffrey KisukyeHannington BalukuFrank Nobert MwiineChristine F NajjukaPublished in: BMC infectious diseases (2019)
Enterococcus species are frequent in clinical specimens at Mulago Hospital but they are highly susceptible to common antibiotics especially ampicillin. While vancomycin resistant enterococcal (VRE) isolates of E. faecium and E. faecalis are rare in the hospital and frequency of multidrug resistance is low, non-faecium and non-faecalis VRE isolates (i.e. E. gallinarum/casseliflavus) are frequent, some with VanA/VanB (high-level) vancomycin resistance. Therefore, species-level identification of enterococci is necessary in resource limited settings to guide infection control and treatment of enterococcal infections.
Keyphrases
- methicillin resistant staphylococcus aureus
- genetic diversity
- healthcare
- acute care
- adverse drug
- primary care
- staphylococcus aureus
- genome wide
- emergency department
- gene expression
- escherichia coli
- dna methylation
- quality improvement
- electronic health record
- combination therapy
- biofilm formation
- cystic fibrosis
- smoking cessation
- replacement therapy
- genome wide identification
- fine needle aspiration