COVID-19 Outcomes and Genomic Characterization of SARS-CoV-2 Isolated From Veterans in New England States: Retrospective Analysis.
Megan LeeYa Haddy SallahMary E PetroneMatthew RingerDanielle CosentinoChantal B F VogelsJoseph R FauverTara D AlpertNathan D GrubaughShaili GuptaPublished in: JMIRx med (2021)
In a cohort of veterans from the six New England states with a mean age of 63 years and a high comorbidity burden, age was the largest predictor of hospitalization, peak disease severity, and mortality. Non-White veterans were more likely to be hospitalized, and patients who required oxygen on admission were more likely to have severe disease and higher rates of mortality. Multiple SARS-CoV-2 lineages were distributed in patients in New England early in the COVID-19 era, mostly related to viruses from New York State with D614G mutation.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- coronavirus disease
- end stage renal disease
- cardiovascular events
- ejection fraction
- newly diagnosed
- risk factors
- emergency department
- chronic kidney disease
- prognostic factors
- cardiovascular disease
- type diabetes
- early onset
- adipose tissue
- patient reported outcomes
- coronary artery disease
- glycemic control
- weight loss