Identification of new risk loci shared across systemic vasculitides points towards potential target genes for drug repurposing.
Lourdes Ortiz-FernándezElio G CarmonaMartin KerickPaul LyonsFrancisco David CarmonaRaquel López MejíasChiea Chuen KhorPeter C GraysonEnrico TombettiLindi JiangHaner DireskeneliGuher Saruhan-DireskeneliJosé-Luis Callejas-RubioAugusto VaglioCarlo SalvaraniHernández-Rodríguez JoséMaria Cinta CidAnn W MorganPeter A MerkelDavid BurgnerKenneth Gc SmithMiguel Angel González-GayAmr H SawalhaJavier MartínAna MarquezPublished in: Annals of the rheumatic diseases (2023)
We identified new shared risk loci with functional impact in vasculitis and pinpointed potential causal genes, some of which could represent promising targets for the treatment of vasculitis.