Colistin Resistance in Aeromonas spp.
Luis Uriel Gonzalez-AvilaMiguel Angel Loyola-CruzCecilia Hernández-CortezJuan Manuel Bello-LopezGraciela Castro-EscarpulliPublished in: International journal of molecular sciences (2021)
The increase in the use of antimicrobials such as colistin for the treatment of infectious diseases has led to the appearance of Aeromonas strains resistant to this drug. However, resistance to colistin not only occurs in the clinical area but has also been determined in Aeromonas isolates from the environment or animals, which has been determined by the detection of mcr genes that confer a resistance mechanism to colistin. The variants mcr-1, mcr-3, and mcr-5 have been detected in the genus Aeromonas in animal, environmental, and human fluids samples. In this article, an overview of the resistance to colistin in Aeromonas is shown, as well as the generalities of this molecule and the recommended methods to determine colistin resistance to be used in some of the genus Aeromonas.