The Validity of Serum Alkaline Phosphatase to Identify Nutritional Rickets in Nigerian Children on a Calcium-Deprived Diet.
Thomas D ThacherChristopher T SemposRamon A Durazo-ArvizuPhilip R FischerCraig Frank MunnsJohn M PettiforPublished in: The Journal of clinical endocrinology and metabolism (2021)
An AP > 350 U/L effectively discriminated between Nigerian children with and without nutritional rickets. AP is a low-cost biochemical test that could be used to screen for nutritional rickets, but cutoff values require validation in other populations, and laboratory values need to be standardized for widespread population studies.