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Exploring the relationship between intron retention and chromatin accessibility in plants.

Fahad UllahMichael HamiltonAnireddy S N ReddyAsa Ben-Hur
Published in: BMC genomics (2018)
In this study we have established an association between IR and chromatin accessibility, and presented a mechanistic hypothesis that explains the observed association from the perspective of the co-transcriptional nature of splicing. Furthermore, we identified conserved sequence elements for DNA-binding proteins that affect splicing.
Keyphrases
  • transcription factor
  • gene expression
  • dna damage
  • genome wide
  • circulating tumor
  • cell free
  • dna methylation
  • heat shock