ki67 nuclei detection and ki67-index estimation: a novel automatic approach based on human vision modeling.
Barbara Rita BarricelliElena CasiraghiJessica GliozzoVeronica HuberBiagio Eugenio LeoneAlessandro RizziBarbara VerganiPublished in: BMC bioinformatics (2019)
The evaluation of the computed results, both through experts' visual assessments and through the comparison of the computed indexes with those of experts, proved that the prototype is promising, so that experts believe in its potential as a tool to be exploited in the clinical practice as a valid aid for clinicians estimating the ki67-index. The MATLAB source code is open source for research purposes.