Association of macular pigment optical density with retinal layer thicknesses in eyes with and without manifest primary open-angle glaucoma.
Thomas LawlerJ A MaresZhe LiuCatherine ThuruthumalyTyler EtheridgeThasarat S VajaranantAmitha DomalpallyBilly R HammondRobert B WallaceLesley F TinkerMarine NalbandyanBarbara E K KleinYao Liunull nullnull nullPublished in: BMJ open ophthalmology (2023)
We observed a positive association between MPOD and central subfield GCC thickness 15 years later. MPOD was positively associated with peripapillary RNFL superior and temporal quadrant thicknesses among eyes with manifest POAG. Our results linking low MPOD to retinal layers that are structural indicators of early glaucoma provide further evidence that carotenoids may be protective against manifest POAG.