Cancer of unknown primary (CUP) through the lens of precision oncology: a single institution perspective.
L WeissK HeinrichD ZhangK DormanK RühlmannK HasselmannF KlauschenJ KumbrinkA JungM RudeliusA MockSteffen OrmannsW G KunzD RoesslerG BeyerS CorradiniL HeinzerlingM HaasM von Bergwelt-BaildonS BoeckV HeinemannChristoph Benedikt WestphalenPublished in: Journal of cancer research and clinical oncology (2023)
CGP and subsequent presentation to a molecular tumor board led to a high rate of therapeutic recommendations in patients with CUP. Recommendations were only implemented at a low rate; however, late GCP diagnostic and, respectively, MTB referral were found more frequent for the patients with implemented treatment. This contrast underscores the need for early implementation of CGP into the management of CUP patients.
Keyphrases
- primary care
- end stage renal disease
- newly diagnosed
- ejection fraction
- mycobacterium tuberculosis
- clinical practice
- papillary thyroid
- magnetic resonance
- palliative care
- patient reported outcomes
- pulmonary tuberculosis
- prognostic factors
- squamous cell carcinoma
- quality improvement
- combination therapy
- patient reported
- lymph node metastasis